THE CORRELATION BETWEEN THE MOLECULAR-STRUCTURES OF O-ETHYL, N-ISOPROPYL PHOSPHORO(THIOUREIDO)THIOATES AND THEIR RETARDATION FACTORS IN HPTLC

Authors
WANG QS YAN BW YANG HZ
Citation
Qs. Wang et al., THE CORRELATION BETWEEN THE MOLECULAR-STRUCTURES OF O-ETHYL, N-ISOPROPYL PHOSPHORO(THIOUREIDO)THIOATES AND THEIR RETARDATION FACTORS IN HPTLC, JPC. Journal of planar chromatography, modern TLC, 10(2), 1997, pp. 118-120
Citations number
10
Categorie Soggetti
Chemistry Analytical
Journal title
JPC. Journal of planar chromatography, modern TLC → ACNP
ISSN journal
09334173
Volume
10
Issue
2
Year of publication
1997
Pages
118 - 120
Database
ISI
SICI code
0933-4173(1997)10:2<118:TCBTMO>2.0.ZU;2-R
Abstract
A computer-assisted retardation factor prediction system (RPS) was inv estigated for HPTLC of sixteen O-ethyl, N-isopropyl, phosphoro(thioure ido) thioates. The system is based on the use of three physicochemical parameters (hydrophobicity, II, substituent length, L, and substituen t maximum width, B-5) which have high correlation with retardation fac tor (R-F) in HPTLC. The RPS was evaluated by comparing measured R-F va lues with those predicted. Good agreement was obtained between predict ed data and experimental results.