MULTIFOCAL SEROUS CYSTADENOMA OF THE PANCREAS - A CASE-REPORT AND REVIEW OF THE LITERATURE

Serous cystadenoma of the pancreas is usually unifocal; multifocal tum ors are rare. We report a case of multifocal serous cystadenoma of the pancreas in a 48-yr-old female complaining of general malaise. Serum tumor markers, such as CA 19-9, DUPAN-2, and Span-1, were elevated. Ab dominal ultrasound (US) and computed tomography (CT) scans revealed tw o distinct cystic masses in the head and body of the pancreas, respect ively. The patient underwent total pancreatectomy. The resected pancre as contained two discrete cystic masses in the head and body; no solid components were observed. Microscopically, the inner surfaces of the cysts were evenly lined by a single layer of low cuboidal or significa ntly attenuated epithelial cells containing clear cytoplasm and abunda nt glycogen without other morphological alterations. The histogenesis of serous cystadenoma is not clear; multicentric tumors may be helpful in understanding histogenesis.