After multiple cases of chronic diarrhea and weight loss in a farmed e
lk herd, 3 yearlings and 1 adult elk with similar clinical signs were
euthanatized and necropsied. Gross and histologic evidence of paratube
rculosis were found in the yearlings. Evidence of serum antibody to My
cobacterium paratuberculosis was detected in the 2 elk with the most d
isseminated infection. Acid-fast organisms were isolated from multiple
organs in all It elk and identified as M paratuberculosis by DNA prob
e. Thirty-five percent of 1 calf crop (n = 31) died or were euthanatiz
ed because of paratuberculosis before they were 2 years old. The organ
ism was believed to have been spread by standing water that was used b
y calves as a wallow and a source of drinking water. The water was bel
ieved to have been contaminated by an infected adult female elk introd
uced to the herd just before calving season.