Oa. Kazakova et al., INTERACTION OF PROTEINS WITH THE SURFACE OF DISPERSED SILICA IN AQUEOUS SUSPENSIONS, Colloid journal of the Russian Academy of Sciences, 60(5), 1998, pp. 563-567
The adsorption of bovine serum albumin on the dispersed silica surface
from aqueous medium was studied. Protein adsorption is virtually inde
pendent of the storage time of the silica suspension. The effects of t
he solvation of dipeptides modeling albumin fragments, and their inter
action with =Si-OH groups of silica in both molecular and zwitter-ioni
c forms were considered. It was established that the maximum contribut
ion to the stabilization of adsorption complexes is made by the =SiO-.
.. H+NR and =SiO(H) ... H+NRCOO- bonds.