ON STEROIDS - PART CCCXCVII - LONG-RANGE EFFECT OF 17-SUBSTITUENTS IN3-OXO STEROIDS ON 4,5-DOUBLE BOND HYDROGENATION

Authors
SIDOVA R STRANSKY K KASAL A SLAVIKOVA B KOHOUT L
Citation
R. Sidova et al., ON STEROIDS - PART CCCXCVII - LONG-RANGE EFFECT OF 17-SUBSTITUENTS IN3-OXO STEROIDS ON 4,5-DOUBLE BOND HYDROGENATION, Collection of Czechoslovak Chemical Communications, 63(10), 1998, pp. 1528-1542
Citations number
22
Categorie Soggetti
Chemistry
Journal title
Collection of Czechoslovak Chemical Communications → ACNP
ISSN journal
00100765
Volume
63
Issue
10
Year of publication
1998
Pages
1528 - 1542
Database
ISI
SICI code
0010-0765(1998)63:10<1528:OS-PC->2.0.ZU;2-W
Abstract
The long-range effect of substituents in the 17-position on the hydrog enation of double bond of the steroidal Delta(4)-3-ketones in acetic a cid on a platinum catalyst is described in a series of testosterone (1 ) and epitestosterone (5) esters with carboxylic acids of varying alky l chain length. The ratio 5 alpha- to 5 beta-products is affected by t he nature of substituents in the position 17.