Ajp. Sandison et al., ICU PROTOCOL MAY AFFECT THE OUTCOME OF NON-ELECTIVE ABDOMINAL AORTIC-ANEURYSM REPAIR, European journal of vascular and endovascular surgery, 16(4), 1998, pp. 356-361
Objectives: to compare the outcome of patients undergoing non-elective
abdominal aortic aneurysm repair at two hospitals under the care of a
single vascular surgeon. Design: prospective and retrospective audit
of 6 years of emergency and urgent infrarenal abdominal aortic aneurys
m surgery. Setting: Lewisham and North Southwark Health Authority. Sub
jects: one hundred and forty-five patients who underwent emergency (46
) or urgent (99) repair of an abdominal aortic aneurysm. Primary outco
me measure: hospital mortality. Secondary outcome measures: acute rena
l failure, intensive care and hospital length of stay distal ischaemia
and return to theatre. Results: mortality was higher at hospital 2 th
an hospital 1 (28% vs. 9%, p = 0.0068). There was no significant diffe
rence in age, sex, cardiac history, hypertension, diabetes, smoking, r
enal impairment (all p>0.05). There was no difference in operation tim
e, blood loss and base excess at the end of surgery between the two gr
oups (all p>0.05). APACHE II scores on admission to ICU were similar i
n hospital 1 and hospital 2 (median 16 vs. 14, p>0.03). Pulmonary arte
ry catheters were placed in 18% of patients at hospital 1 compared wit
h 96% at hospital 2. Patients at hospital 2 received more crystalloid
(median 2990 vs. 2300 ml divided by, more colloid (median 4775 vs. 150
0 ml), and more inotropes (median 1 vs. 0) than those at hospital 1 in
their first 24 h on ICU (all p<0.001). The volume of urine passed in
the first 24 h was similar (median 2410 vs. 2000 ml, p = 0.12) yet the
incidence of acute renal failure was higher at hospital 2 compared wi
th hospital 1 (30% vs. 6%, p = 0.001). ICU length of stay of survivors
was longer at hospital 2 (median 3 vs. 2 days, p = 0.0018) as was hos
pital length of stay (median 17.5 vs. 12 days, p = 0.0002). Conclusion
s: the outcome at both hospitals is at least as good as other reported
series, but it is interesting to note that the hospital which used le
ss pulmonary artery catheters and less intervention (in the form of co
lloid and inotropes) showed a reduced mortality. These data may be imp
ortant is assessing the different therapeutic strategies employed post
operatively in the ICU.