W. Eng et Pr. Cohen, NEVUS WITH FAT - CLINICAL CHARACTERISTICS OF 100 NEVI CONTAINING MATURE ADIPOSE-CELLS, Journal of the American Academy of Dermatology, 39(5), 1998, pp. 704-711
Background: The presence of mature adipose cells among the dermal mela
nocytes of nevi (nevi with fat) has previously been reported. However,
its clinical features are not well characterized. Objective: Our goal
was to develop a better clinical understanding and insight into the h
istogenesis of nevi with fat by characterizing the patients' age, sex,
height, weight, and location of lesion. Methods: This was a prospecti
ve study of 100 nevi with fat from 89 patients over an 18-month period
. Results: Nevi with fat occur 4 times more commonly in women than men
. They were diagnosed most often in patients between the ages of 40 to
49 years. The most frequent location is the head and neck. Most nevi
with fat are intradermal. Conclusion: The appearance of fat within nev
i is probably a multifactorial process. Age, weight, and sun exposure
may be factors associated with the occurrence of nevi with fat.