IN-VITRO SENSITIVITY TO RONIDAZOLE OF DIFFERENT TRICHOMONAS-GALLINAE STRAINS ISOLATED FROM PIGEONS

The minimal cytocidal concentrations of ronidazole (CMT) were determin ed in vitro and the cytopathogenic effects on chicken fibroblast cell cultures were evaluated for 31 strains of T. gallinae isolated from pi geons of different lofts frequenting the Avian clinic. The level of re sistance in vitro corresponding to the in vivo resistance has been det ermined and is equal to 80 mu g/ml. Forty-five percent of the strains have a CMT of 40 mu g/ml, very close to the resistance level, it is re commended to take care of the use of nitroimidazoles to control tricho moniasis in pigeons. The treatments should be reserved only to clinica lly affected pigeons and should be given during a minimal period of fi ve to seven days at a therapeutic dose of 100 to 150 mg ronidazole in one liter of drinking water.