Cc. Horn et al., EVIDENCE THAT HEMOLYMPH GLUCOSE IN APLYSIA-CALIFORNICA IS REGULATED BUT DOES NOT AFFECT FEEDING-BEHAVIOR, Behavioral neuroscience, 112(5), 1998, pp. 1258-1265
Hemolymph glucose increased following a meal of a commercially availab
le dried seaweed (laver) in Aplysia californica (Aplysia). Glucose inj
ected into the hemocoel did not affect meal size, bite latencies, swal
lowing rate, or 24-hr food intake. The authors found that injection of
a homogenate of nerves containing a putative Aplysia insulin-like sub
stance decreased hemolymph glucose. The nerve homogenate, however, did
not affect feeding behavior. Injection of 2-deoxy-D-glucose was found
to increase hemolymph glucose, an indication of gluco-privation, but
instead of increasing feeding it either had no effect or, at high dose
s, debilitated animals and interfered with feeding. These studies sugg
est that glucose may be physiologically regulated in Aplysia, but it d
oes not appear to play a role in the control of feeding behavior.