BRONCHIOLITIS OBLITERANS ORGANIZING PNEUMONIA IN 3 CHILDREN WITH ACUTE LEUKEMIAS TREATED WITH CYTOSINE-ARABINOSIDE AND ANTHRACYCLINES

Authors
BATTISTINI E DINI G SAVIOLI C MORANDO A GANDOLFO A KOTITSA Z GARAVENTA A ROSSI GA
Citation
E. Battistini et al., BRONCHIOLITIS OBLITERANS ORGANIZING PNEUMONIA IN 3 CHILDREN WITH ACUTE LEUKEMIAS TREATED WITH CYTOSINE-ARABINOSIDE AND ANTHRACYCLINES, The European respiratory journal, 10(5), 1997, pp. 1187-1190
Citations number
28
Categorie Soggetti
Respiratory System
Journal title
The European respiratory journal → ACNP
ISSN journal
09031936
Volume
10
Issue
5
Year of publication
1997
Pages
1187 - 1190
Database
ISI
SICI code
0903-1936(1997)10:5<1187:BOOPI3>2.0.ZU;2-T
Abstract
Bronchiolitis obliterans organizing pneumonia (BOOP) is a clinicopatho logical entity with well-defined diagnostic criteria, which can be idi opathic or produced by a variety of biological processes, We describe the occurrence of BOOP in three children, one with acute lymphoblastic leukaemia and two with acute promyelocytic leukaemia. In the three pa tients, BOOP developed 10-20 days after a course of therapy with cytos ine arabinoside and anthracyclines. The possible relationships between the small conducting airway lesions, lung toxic reaction to the drugs and/or nonidentified infectious agents are discussed.