BULLOUS PEMPHIGOID PRESENTING AS EXFOLIATIVE ERYTHRODERMA

Several unusual clinical presentations of bullous pemphigoid have been described such as localized, vesicular, vegetating, nodular, and sine bulla pemphigoid. Patients with erythroderma who fulfill diagnostic c riteria for bullous pemphigoid and in whom bullae develop have been re ported. We describe a patient with exfoliative erythroderma without an y blistering in whom a diagnosis of bullous pemphigoid was based on ex amination of a biopsy specimen. Circulating antibodies to the basement membrane zone, with an epidermal pattern on salt split skin, and the presence of eosinophilic spongiosis in the skin biopsy specimen suppor ted the diagnosis.