Objective. The aim of this study was to evaluate whether the level of
some immune markers changed in soccer players during pre-season and du
ring playing-season. Design.,Sn observational study for one soccer sea
son (one gear), Setting, Professional soccer players. Participants. Th
irteen professional soccer players (age: 26.3+/-3.7 Sears). Measures.
The effect of 11 months of soccer training sessions and matches on cir
culating leukocyte and lymphocyte subpopulations was investigated. Blo
od samples were taken before the season and also 6 weeks, 6 months and
11 months later. All samples were taken at 08:00h. Results, Total lym
phocyte counts did not change in all samples. During the pre-season, h
owever, the concentrations of some inflammatory lymphocyte subpopulati
ons were changed: CD4CD45RA+ was elevated and CD57 and CD8CD57 showed
a significant decrease (p<0.05), At the end of the competitive period,
CD4 and CD8 were increased. At the end of the season there were signi
ficant changes in some immune cells: total leukocyte and neutrophil nu
mber and CD8+ cell concentration was increased compared to pre-season
values and the CD4/CD8 ratio was decreased. Conclusions. The results s
uggest that athletes exposed to a longterm training periods can exhibi
t variations in some immune cells. The clinical significance of these
variations requires more detailed investigation.