The origin of the resistivity anomaly at 120 K in the layered pnictide
oxide Na2Ti2Sb2O is discussed on the basis of tight-binding band stru
cture calculations. The Fermi surface of this material is shown to res
ult from the superposition of a two-dimensional and four pseudo-one-di
mensional components. It is proposed that the resistivity anomaly is a
ssociated with a Fermi surface instability of these pseudo-one-dimensi
onal portions leading to a periodic lattice distortion.