THE USE OF GLYCOSYL-H-PHOSPHONATES FOR THE SYNTHESIS OF NUCLEOSIDE GLYCOSYL PHOSPHATES

Authors
IVANOVA IA UTKINA NS SHIBAEV VN
Citation
Ia. Ivanova et al., THE USE OF GLYCOSYL-H-PHOSPHONATES FOR THE SYNTHESIS OF NUCLEOSIDE GLYCOSYL PHOSPHATES, Bioorganiceskaa himia, 24(9), 1998, pp. 710-714
Citations number
26
Categorie Soggetti
Chemistry Inorganic & Nuclear",Biology
Journal title
Bioorganiceskaa himia → ACNP
ISSN journal
01323423
Volume
24
Issue
9
Year of publication
1998
Pages
710 - 714
Database
ISI
SICI code
0132-3423(1998)24:9<710:TUOGFT>2.0.ZU;2-I
Abstract
A new method of synthesis of nucleoside 5'-glycosyl phosphates by coup ling nucleosides and acylated glycosyl H-phosphonates followed by oxid ation and deacylation is proposed. By this method, conjugates of 3'-az ido-3'-deoxythymidine 5'-phosphate with 2-acetamido-2-deoxy-alpha-D-gl ucopyranose, alpha-D-mannopyranose, and beta-D-galactopyranose were pr epared.