NEW CHIRAL AMINOPHOSPHINE CARBOXYPHOSPHINITE LIGANDS (AMPCP) - SYNTHESIS AND APPLICATION IN ASYMMETRIC HYDROGENATION AND HYDROFORMYLATION

Authors
NAILI S MORTREUX A AGBOSSOU F
Citation
S. Naili et al., NEW CHIRAL AMINOPHOSPHINE CARBOXYPHOSPHINITE LIGANDS (AMPCP) - SYNTHESIS AND APPLICATION IN ASYMMETRIC HYDROGENATION AND HYDROFORMYLATION, Tetrahedron : asymmetry, 9(19), 1998, pp. 3421-3430
Citations number
39
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
9
Issue
19
Year of publication
1998
Pages
3421 - 3430
Database
ISI
SICI code
0957-4166(1998)9:19<3421:NCACL(>2.0.ZU;2-Z
Abstract
The synthesis of the first three aminophosphine-carboxyphosphinite dip hosphanes derived directly from alpha-amino acids is presented. These ligands were applied in the asymmetric hydrogenation of dihydro-2,4-di methyl-2,3-furandione giving the corresponding pantolactone with up to 42% ee. They were also involved, in association with platinum, in the asymmetric hydroformylation of styrene giving the branched aldehyde w ith low ee (<5%). (C) 1998 Elsevier Science Ltd. All rights reserved.