BACKGROUND: Ganglioneuroblastoma is commonly observed in children but
rarely in adults. Therapy and prognosis are not well defined in adults
. CASE REPORT: We report the case of a female adult who developed a ga
nglioneuroblastoma of the left adrenal gland with liver metastasis. Su
rgical treatment combined with radio and chemotherapy led to complete
remission. DISCUSSION: The outcome in our patient and data reported in
the literature suggest that a multidisciplinary approach is necessary
and that initial surgical resection should be performed whenever poss
ible. Adjuvant radiotherapy or chemotherapy have been shown to be some
what effective in children but their true impact in adults remains to
be ascertained. Follow-up after resection should include physical exam
ination, assay of adrenal derivatives in plasma and urine and imaging.