Descending necrotizing mediastinitis (DNM) is a potentially life-threa
tening complication that can develop after an oropharyngeal infection.
Patients with DNM are usually treated with mediastinal drainage throu
gh a cervical or transthoracic approach, as well as by the systemic ad
ministration of antibiotics. We report herein the cases of two patient
s we recently treated for DNM. In the first patient, the DNM was limit
ed to the upper mediastinum, and cervicomediastinal drainage was perfo
rmed. In the second patient, the mediastinitis spread below the trache
al bifurcation down into the lower mediastinum, and an abscess was dra
ined through a thoracotomy approach. The principles of the surgical ap
proach for DNR I are discussed, with a brief review of the literature
following these case reports.