CD40 AND EPITHELIAL-CELLS - ACROSS THE GREAT DIVIDE

Authors
YOUNG LS ELIOPOULOS AG GALLAGHER NJ DAWSON CW
Citation
Ls. Young et al., CD40 AND EPITHELIAL-CELLS - ACROSS THE GREAT DIVIDE, Immunology today, 19(11), 1998, pp. 502-506
Citations number
38
Categorie Soggetti
Immunology
Journal title
Immunology today → ACNP
ISSN journal
01675699
Volume
19
Issue
11
Year of publication
1998
Pages
502 - 506
Database
ISI
SICI code
0167-5699(1998)19:11<502:CAE-AT>2.0.ZU;2-3
Abstract
The widespread expression of CD40 in normal epithelial cells and carci noma cells suggests that this receptor has important, additional influ ences beyond that of regulating immune responses. Here, Lawrence Young and colleagues discuss the effect of CD40 ligation on epithelial cell s and consider the role of this pathway in the pathogenesis and treatm ent of carcinomas.