NEUTROPHIL-KUPFFER-CELL INTERACTION IN HOST DEFENSES TO SYSTEMIC INFECTIONS

Authors
GREGORY SH WING EJ
Citation
Sh. Gregory et Ej. Wing, NEUTROPHIL-KUPFFER-CELL INTERACTION IN HOST DEFENSES TO SYSTEMIC INFECTIONS, Immunology today, 19(11), 1998, pp. 507-510
Citations number
44
Categorie Soggetti
Immunology
Journal title
Immunology today → ACNP
ISSN journal
01675699
Volume
19
Issue
11
Year of publication
1998
Pages
507 - 510
Database
ISI
SICI code
0167-5699(1998)19:11<507:NIIHDT>2.0.ZU;2-D
Abstract
Most relevant textbooks characterize phagocytosis by Kupffer cells as the principal mechanism for clearing bacterial pathogens from the bloo dstream and eliminating them from the liver. Here, Stephen Gregory and Edward Wing discuss recent evidence indicating that the actual mechan ism is far more complicated, dependent upon the complex interaction of Kupffer cells with neutrophils that immigrate into the liver followin g infection.