Objective The aim of this study was to determine the incidence in an u
nselected population of a rod-like structure on the fetal upper lip (c
alled a 'mustache') which we had previously observed as an incidental
finding. A secondary aim was to determine whether this was associated
with any abnormalities or abnormal outcomes. Design Prospective non-ra
ndomized study. Subjects Three thousand consecutive fetuses from an un
selected population were scanned by one sonologist. Method Transvagina
l ultrasound examinations were performed at 14-16 weeks' gestation. Re
peat sonographic examinations were performed at 20-22 weeks' gestation
in cases where a mustache was detected, and these neonates were exami
ned by a pediatrician after delivery. Results Seven of 3000 fetuses ha
d a mustache-like structure on the upper lip. The 'mustache' disappear
ed laser in gestation. No anomaly of the upper lip was detected after
birth in these fetuses. Conclusion A mustache-like structure on the fe
tal upper lip in early pregnancy probably represents a normal variant
of lip development. It is likely to represent a delay in the normal pr
ocess of lip fusion during embryonic life.