Wi. Campbell et al., BALANCED PREEMPTIVE ANALGESIA - DOES IT WORK - A DOUBLE-BLIND, CONTROLLED-STUDY IN BILATERALLY SYMMETRICAL ORAL-SURGERY, British Journal of Anaesthesia, 81(5), 1998, pp. 727-730
We studied 32 patients undergoing bilateral symmetrical lower third mo
lar surgery under general anaesthesia to determine if the combined eff
ects of pre-emptive local anaesthetic block using 0.5% bupivacaine, to
gether with i.v. tenoxicam and alfentanil had any benefits over postop
erative administration. Patients acted as their own controls and were
allocated randomly to have surgery start on one side, the second side
always being the pre-emptive side. Difference in pain intensity betwee
n the two sides was determined using visual analogue scales completed
by each individual at 6 h, and at 1, 3 and 6 days after operation. A l
ong-form McGill pain questionnaire was also used to assess difference
in pain intensity between the two sides on the morning after surgery.
There was no significant difference in pain intensity at any time afte
r surgery. Our findings indicate that the combined use of pre-emptive
analgesia from 0.5% bupivacaine, tenoxicam and alfentanil did not redu
ce postoperative pain intensity in patients undergoing molar exodontia
.