A FORMAL TOTAL ASYMMETRIC-SYNTHESIS OF (-THIENAMYCIN())

Authors
DAVIES SG HEDGECOCK CJR MCKENNA JM
Citation
Sg. Davies et al., A FORMAL TOTAL ASYMMETRIC-SYNTHESIS OF (-THIENAMYCIN()), Tetrahedron : asymmetry, 6(10), 1995, pp. 2507-2510
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
6
Issue
10
Year of publication
1995
Pages
2507 - 2510
Database
ISI
SICI code
0957-4166(1995)6:10<2507:AFTAO(>2.0.ZU;2-L
Abstract
Synthesis of an enantiomerically pure intermediate to (+)-thienamycin is presented: the pivotal reaction in this sequence is the highly dias tereoselective Michael addition of a differentially protected lithium amide.