MECHANISTIC ANALYSIS AND CHEMOPREVENTION OF PANCREATIC CARCINOGENESIS

Thirteen presentations given at a workshop held in November 1997, unde r the sponsorship of The Princess Takamatsu Cancer Research Fund in Na ra, Japan, are summarized. Topics include studies of initiation, promo tion, and chemoprevention in animal models of pancreatic carcinogenesi s, molecular and histopathologic studies of human carcinomas, and epid emiologic studies. A recurring focus was to explore ways that knowledg e of molecular mechanisms of carcinogenesis and molecular abnormalitie s in carcinomas can guide approaches for prevention and treatment of p ancreatic cancer.