ENANTIOSELECTIVE SYNTHESIS OF SUCCINIC ACIDS AND GAMMA-LACTONES VIA PALLADIUM-CATALYZED ALLYLIC SUBSTITUTION-REACTIONS

Authors
DAWSON GJ WILLIAMS JMJ COOTE SJ
Citation
Gj. Dawson et al., ENANTIOSELECTIVE SYNTHESIS OF SUCCINIC ACIDS AND GAMMA-LACTONES VIA PALLADIUM-CATALYZED ALLYLIC SUBSTITUTION-REACTIONS, Tetrahedron : asymmetry, 6(10), 1995, pp. 2535-2546
Citations number
36
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
6
Issue
10
Year of publication
1995
Pages
2535 - 2546
Database
ISI
SICI code
0957-4166(1995)6:10<2535:ESOSAA>2.0.ZU;2-E
Abstract
The palladium catalysed reaction between nan-symmetrical allyl acetate s and sodiodimethylmalonate proceeds in high yields and enantioselecti vities (up to 99% ee) using a diphenylphosphinoaryl oxazoline ligand. The so-formed substitution products are transformed into enantiomerica lly enriched succinic acids and also into enantiomerically enriched ga mma-lactones.