EFFECTS OF MAGNETIC-FIELD ON HYALURONIDASE AND BETA-D-GLUCURONIDASE ACTIVITY AND ON HYALURONIC-ACID AND CHONDROITIN SULFATE LEVELS IN RAT-LIVER

The livers of rats exposed to a static magnetic field (0.49 T) and an extremely low frequency (ELF) magnetic field (50 Hz, 0.018 T) have bee n studied for any alterations in hyaluronic acid (HA), and chondroitin sulfate (ChS) content as well as for any changes in the activity of h yaluronidase (EC 3.2.1.35) and beta-D-glucuronidase (EC 3.2.1.31). The livers of animals exposed to ELF magnetic fields were found to have d ecreased HA and increased ChS content. Hyaluronidase activity was incr eased and that of beta-D-glucuronidase decreased. No changes were obse rved in animals exposed to a static magnetic field. The results of the present study may suggest that the metabolism of connective tissue ba sic substance is significantly affected by the ELF magnetic field.