Km. Fairfield et al., PATTERNS OF USE, EXPENDITURES, AND PERCEIVED EFFICACY OF COMPLEMENTARY AND ALTERNATIVE THERAPIES IN HIV-INFECTED PATIENTS, Archives of internal medicine, 158(20), 1998, pp. 2257-2264
Background: Complementary and alternative medicine (CAM) use is common
in the general population, accounting for substantial expenditures. A
mong patients with human immunodeficiency virus (HIV) infection, few d
ata are available on the prevalence, costs, and patterns of alternativ
e therapy use. Methods: We carried out detailed telephone surveys and
medical chart reviews for 289 active patients with HIV in a general me
dicine practice at a university-based teaching hospital in Boston, Mas
s. Data were collected on prevalence and patterns of CAM use, out-of-p
ocket expenditures, associated outcomes, and correlates of CAM use. Re
sults: Of 180 patients who agreed to be interviewed, 122 (61.8%) used
herbs, vitamins, or dietary supplements, 81 (45.0%) visited a CAM prov
ider, and 43 (23.9%) reported using marijuana for medicinal purposes:i
n the previous year. Patients who saw CAM providers made a median of 1
2 visits per year to these providers compared with 7 visits per year t
o their primary care physician and nurse practitioner. Mean yearly out
-of-pocket expenditures for CAM users totaled $938 for all therapies.
For the main reason CAM was used, respondents found therapies ''extrem
ely'' or ''quite a bit'' helpful in 81 (81.0%) of 100 reports of suppl
ement use, in 76 (65.5%) of 116 reports of CAM provider use, and in 27
(87%) of 31 reports of marijuana use. In multivariable models, colleg
e education (odds ratio [OR]=3.7, 95% confidence interval [CI] = 1.9-7
.1) and fatigue (OR = 2.7, 95% CI = 1.4-5.2) were associated with CAM
provider use; memory loss (OR = 2.3, 95% CI = 1.1-4.8) and fatigue (OR
=0.4, 95% CI=0.2-0.9) were associated with supplement use; and weight
loss (OR= 2.6, 95% CI=1.2-5.6) was associated with marijuana use. Con
clusions: Patients with HIV infection use CAM, including marijuana, at
a high rate; make frequent visits to CAM providers; incur substantial
expenditures; and report considerable improvement with these treatmen
ts. Clinical trials of frequently used CAMs are needed to inform physi
cians and patients about therapies that may have measurable benefit or
measurable risk.