CLONING, CHARACTERIZATION AND EXPRESSION OF THE APOLIPOPROTEIN-A-I GENE IN THE SEA BREAM (SPARUS-AURATA)

Citation
L. Llewellyn et al., CLONING, CHARACTERIZATION AND EXPRESSION OF THE APOLIPOPROTEIN-A-I GENE IN THE SEA BREAM (SPARUS-AURATA), Biochimica et biophysica acta, N. Gene structure and expression, 1442(2-3), 1998, pp. 399-404
Citations number
19
Categorie Soggetti
Biology,Biophysics
ISSN journal
01674781
Volume
1442
Issue
2-3
Year of publication
1998
Pages
399 - 404
Database
ISI
SICI code
0167-4781(1998)1442:2-3<399:CCAEOT>2.0.ZU;2-R
Abstract
A full length cDNA clone representing apolipoprotein A-I was isolated from a sea bream (Sparus aurata) liver library. The clone encodes a 26 1 amino acid protein which shows highest amino acid identity (38%) wit h salmon apolipoprotein A-I. Northern blot analysis showed strong expr ession of a 1.4 kb transcript in liver with lower expression in intest ine. Expression of apolipoprotein A-I in intestine was markedly reduce d by treatment with triiodothyronine (T-3) (C) 1998 Elsevier Science B .V. All rights reserved.