CLINICAL-TRIALS AND THERAPY

Authors
GAUTHIER S
Citation
S. Gauthier, CLINICAL-TRIALS AND THERAPY, Current opinion in neurology, 11(5), 1998, pp. 435-438
Citations number
41
Categorie Soggetti
Neurosciences,"Clinical Neurology
Journal title
Current opinion in neurology → ACNP
ISSN journal
13507540
Volume
11
Issue
5
Year of publication
1998
Pages
435 - 438
Database
ISI
SICI code
1350-7540(1998)11:5<435:>2.0.ZU;2-Z
Abstract
Parallel-group studies have established the efficacy of cholinesterase inhibitors in Alzheimer's disease, at least for short-term cognitive and clinical global enhancement. Noncognitive outcomes are currently u nder scrutiny. Time to reach clinical milestones may be a more useful trial design for new studies aiming to delay appearance or progression of disease. Curt Opin Neurol 11:435-438. (C) 1998 Lippincott Williams & Wilkins.