Naproxen is a commonly used nonsteroidal anti-inflammatory drug (NSAID
) whose side effects include tinnitus and transient hearing loss. Sudd
en sensorineural hearing loss has rarely been reported as a result of
NSAID use. This usually occurs in patients taking other ototoxic medic
ations, with poor renal function, or with autoimmune disease. This art
icle reports the case of an otherwise healthy patient who experienced
permanent sensorineural hearing loss after a brief course of naproxen
and reviews the literature on NSATD-related permanent sensorineural he
aring loss.