Evaluation of pupil diameter is used in many clinical and research fie
lds to aid diagnosis of neurological disorders and to monitor pharmaco
logical effects upon the eye. Methods used to determine pupillary diam
eter have evolved from simple scale measurements to much more complex
systems, supposedly improving accuracy and repeatability. However, man
y techniques are restricted to the consulting room or research laborat
ory due to the size of the equipment, its cost, or the expertise requi
red. We have evaluated a portable pupillometer originally developed by
Broca, capable of precise measurements on fixed, dilated pupils, that
has the potential to be used by unsupervised patients. Luminance leve
ls will still need to be controlled because, although luminance does n
ot influence the mechanics of the pupillometer itself, it significantl
y affects the natural pupil. The pinhole size should ideally be 1.1 mm
in diameter, since smaller pinholes underestimate and larger holes ov
erestimate pupil size. The pupillometer also exhibited reasonable accu
racy in fixed pupils dilated with tropicamide. Pupil measurements were
overestimated by 0.5% using the l.-E mm pinholes (insignificant if th
e pupil can be measured to the nearest 0.25 mm) and both intra- and in
ter-visit repeatabilities were relatively good. The results from this
study therefore indicate that the pinhole pupillometer may be of use i
n pupil research, since it facilitates more frequent pupillary measure
ments over much longer time intervals than are currently achievable. (
C) 1998 The College of Optometrists. Published by Elsevier Science Ltd
. All rights reserved.