REACTIVITY OF SCHIFF-BASE - PART-3 - AMINATION OF 2- 4-HYDROXYBENZYLIDENE-2-AMINOBENZOTHIOZOLE/

The amination reactions of 2-/4-hydroxybenzylidene-2-aminobenzothiazol e (la and Ib respectively) have been kinetically studied in chloroform medium, la is found to react faster than Ib. Both kinetic and spectra l data support aggregation of both la and Ib in the experimental condi tions. Aniline is also found to aggregate in chloroform beyond a limit ing concentration. The higher reactivity of la supports the entrapment mechanism in which aniline molecule is entrapped by Za making it more reactive than Ib. The reactivity of aniline is explained both by intr a and inter molecular catalysis. The curvature in the plot of rate con stant versus [substrate] has been explained by proposing an aggregatio n of the substrates in chloroform.