RECTAL WASHOUT ELIMINATES EXFOLIATED MALIGNANT-CELLS

Citation
Dc. Jenner et al., RECTAL WASHOUT ELIMINATES EXFOLIATED MALIGNANT-CELLS, Diseases of the colon & rectum, 41(11), 1998, pp. 1432-1434
Citations number
22
Categorie Soggetti
Gastroenterology & Hepatology",Surgery
ISSN journal
00123706
Volume
41
Issue
11
Year of publication
1998
Pages
1432 - 1434
Database
ISI
SICI code
0012-3706(1998)41:11<1432:RWEEM>2.0.ZU;2-Y
Abstract
PURPOSE: Irrigation of the rectal stump before anastomosis after resec tion for carcinoma is accepted colorectal surgical practice. However, not all surgeons perform this routinely, and it has never been establi shed conclusively that irrigation of the rectal stump eliminates exfol iated malignant cells or even reduces local recurrence. The patients o f a surgeon whose standard surgical practice involved rectal irrigatio n were compared with those of a surgeon who does not routinely practic e rectal irrigation. METHOD: Ten patients were given rectal washout wi th 200 to 500 mi of normal saline introduced via a Foley catheter per rectum. Ten patients were not given rectal washout. In both groups the anastomosis was performed with a circular stapler, and the stapler an d donuts were rinsed in 200 mi of normal saline. The saline was sent f or cytologic examination and classified as malignant cells seen or no malignant cells seen. The cytopathologist was blinded to the washout s tatus. RESULTS: Of the ten patients who had rectal washout performed, none had malignant cells seen. Of the ten patients who did not have re ctal washout performed, eight had malignant cells seen in the cytology (P = 0.007; two-tailed Fisher's exact probability test). CONCLUSION: Rectal washout eliminates exfoliated malignant cells in the rectum in the vicinity of the anastomosis.