In Japan, mass mortalities of cultured fish due to infections diseases
have been often reported. Among the pathogens, viruses are the most d
evastating infectious agents that afflict fish. This paper reviews the
major viral diseases of cultured marine fish in Japan. The major dise
ases caused by DNA viruses include viral epidermal hyperplasia in flou
nder and herpesviral disease in coho salmon, both caused by a hepesvir
uses and lymphocystis disease and another iridoviral disease in red se
a bream and other marine fishes. The major diseases caused by RNA viru
ses are viral ascites (VA), viral deformity (VD) in yellowtail, both c
aused by a birnavirus (YAV or VDV), erythrocytic inclusion body syndro
me (EIBS) in coho salmon, a rhabdoviral disease in flounder and viral
nervous necrosis (VNN) in striped jack and several other fishes by a n
odavirus. The causative virus of Kuchijirosho in tiger puffer has not
been classified.