HYDROXYAPATITE COATING ON A COLLAGEN MEMBRANE BY A BIOMIMETIC METHOD

The coating of a carbonate-containing hydroxyapatite (HAp) on a nonbio active collagen membrane via a biomimetic method has been investigated , The collagen membranes were soaked in a simulated body fluid (SBF) s olution with and without citric acid, and carbonate-containing HAp for med only in the SBF solution that contained citric acid, The results w ere explained in terms of the strong chelation ability of citric acid with the calcium ion. Practical application may involve the inclusion of citric acid in the SBF solution to promote the formation of HAp on previously nonbioactive collagen membranes.