SYNTHESIS OF 4-TRIFLUOROMETHYL-1,2,4-TRIOXANES, SIMPLIFIED ANALOGS OFARTEMISININ

Authors
PROVOT O MOSKOWITZ H MAYRARGUE J
Citation
O. Provot et al., SYNTHESIS OF 4-TRIFLUOROMETHYL-1,2,4-TRIOXANES, SIMPLIFIED ANALOGS OFARTEMISININ, Journal of fluorine chemistry, 91(2), 1998, pp. 199-201
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear
Journal title
Journal of fluorine chemistry → ACNP
ISSN journal
00221139
Volume
91
Issue
2
Year of publication
1998
Pages
199 - 201
Database
ISI
SICI code
0022-1139(1998)91:2<199:SO4SAO>2.0.ZU;2-7
Abstract
A short synthesis of C-4 trifluoro-substituted 1,2,4-trioxanes with an timalarial potential is reported. This is the first example using a tr ifluorosilylated enol ether function as a protective group for a trifl uoromethyl carbonyl. (C) 1998 Elsevier Science S.A. All rights reserve d.