In the last 30 years, few advances have been made in the management of
tibial stress injuries such as tibial stress fracture and medial tibi
al stress syndrome (MTSS). Tibial overuse injuries are a recognised co
mplication of the chronic, intensive, weight-bearing training commonly
practised by athletic and military populations. Generally, the most e
ffective treatment is considered to be rest, often for prolonged perio
ds. This is a course of action that will significantly disrupt an acti
ve lifestyle, and sometimes end activity-related careers entirely. The
re is now considerable knowledge of the nature of tibial stress injuri
es, such that presently accepted management practices can be criticall
y evaluated and supplemented. Most recent investigations suggest that
tibial stress injuries are a consequence of the repetitive tibial stra
in imposed by loading during chronic weight-bearing activity. Evidence
is presented in this article for an association between repeated tibi
al bending and stress injury as a function of: (i) strain-related mode
lling (in the case of MTSS), and (ii) a strain-related positive feedba
ck mechanism of remodelling (in the case of stress fracture). Factors
that influence the bending response of the tibia to loading are review
ed. Finally, a guide for injury prevention and management based on res
earch observations is presented.