RADIO-IMAGING FOR QUANTITATIVE AUTORADIOGRAPHY IN BIOLOGY

We present here an overview of new in vitro and ex vivo radio-imaging systems developed to overcome the limitations of films and emulsions c urrently used in histological autoradiography experiments. The shortco mings of films for quantitative studies are first introduced. Principl es and performances of each family of imagers are discussed and illust rated in various biological contexts. Finally, perspectives of develop ment including nonradioactive labeling techniques are briefly presente d. NUCL MED BIOL 25;8: 699-704, 1998. (C) 1998 Elsevier Science Inc.