PREVALENCE OF URINARY AND RENAL COMPLICATIONS OF SCHISTOSOMA-HAEMATOBIUM INFECTION IN AN ENDEMIC AREA IN MADAGASCAR

This prospective study was designed to look for and describe urologic and nephrologic consequences of urinary bilharziosis due to schistosom a haematobium in a hyperendemic hotbed in the middle west of Madagasca r. Methodology included clinical examination, kidney and bladder ultra sonography, urine dipsticks and creatininemia. Amongst a population of 574 persons aged 5 years ore more, 436 (76%) had bilharziosis ova in the urine (filtration method). From the clinical point of view, 257 pa tients (58.9%) had microscopic hematuria, 178 (40.8%) had presently an hematuria; 111 patients (25.5%) suffered from dysuria; 18 patients (4 .1%) had [imb oedema when 3 patients had present oedema (0.7%). Among 436 checked people, 267 (61.2%) had an ultrasonography abnormality. In 252, it was bladder wall abnormalities (57.8%). They were wall irregu larities in 182 cases (41.7%); vesico-ureteral reflux in 22 cases (5.3 %); ureteral dilatations in 22 cases (5.3%) and pyelocalyceal dilatati ons in 61 cases (13.9%). Prevalence of proteinuria 75.2% (316 amongst 420 checked people) of whom 5.7% (24 cases) had 5 g/l or more. Hematur ia was found in 352 patients (83.8%) of whom 238 (56.7%) had more than 250 erythrocytes per microliter. Prevalence of leucocyturia was 56.7% (238 cases). Creatininemia was measured in 140 people with positive f iltration, it was normal in all except two patients. This study highli ghts the parallel evolution between parasitic infection and uronephrol ogical manifestations of the disease.