We study super-replication of contingent claims in markets with fixed transaction costs.This can be viewed as a stochastic impulse control problem with a terminal state constraint.The first result in this paper reveals that in reasonable continuous time financial market models the super-replication price is prohibitively costly and leads to trivial buy-and-hold strategies.Our second result derives nontrivial scaling limits of super-replication prices for binomial models with small fixed costs.