Fs. Ordonez et al., ABSENCE OF THE INFERIOR VENA-CAVA CAUSING REPEATED DEEP VENOUS THROMBOSIS IN AN ADULT - A CASE-REPORT, Angiology, 49(11), 1998, pp. 951-956
Agenesis of the inferior vena cava is an uncommon congenital vascular
malformation. Although theoretically it may favor venous stasis, it is
not normally associated with venous thrombosis. The authors found onl
y three reports of the coexistence of both entities, and only one of t
hese rules out the existence of associated hypercoagulability. They re
port the case of a patient with a history of repeated venous thrombosi
s. Magnetic resonance angiography and venography demonstrated complete
agenesis of the inferior vena cava and persistence of a cardinal veno
us system with azygos and hemiazygos continuation, associated with rig
ht renal hypoplasia. Studies ruled out hypercoagulability syndrome, ei
ther primary or secondary to an occult neoplasm. The authors conclude
that venous malformations, although rare, may cause thromboembolic dis
ease, especially in young patients, and that magnetic resonance angiog
raphy is a useful diagnostic alternative to conventional phlebography.