S. Katsiris et al., RESPIRATORY ARREST FOLLOWING INTRATHECAL INJECTION OF SUFENTANIL AND BUPIVACAINE IN A PARTURIENT, Canadian journal of anaesthesia, 45(9), 1998, pp. 880-883
Purpose: To present a case of respiratory arrest following the use of
intrathecal sufentanil and bupivacaine for combined spinal-epidural an
aesthesia in a healthy labouring parturient. Clinical Features: A 20-y
r-old term parturient received 10 mu g sufentanil and 2.5 mg bupivacai
ne intrathecally as part of a combined spinal-epidural technique for l
abour analgesia. She had received no previous analgesics. Twenty-three
minutes after the intrathecal injection she became unresponsive and s
uffered a respiratory arrest. Resuscitation included manual bag/mask v
entilation with oxygen and intravenous naloxone. Conclusion: Respirato
ry arrest is a rare but potentially life-threatening complication asso
ciated with the use of intrathecal opioids for labour analgesia. Vigil
ance in post-procedure patient monitoring is imperative.