T. Matsuo et al., CASE-REPORT - A PATIENT WHO DEVELOPED AN AMEBIC LIVER-ABSCESS DURING TREATMENT WITH INTERFERON, Journal of gastroenterology and hepatology, 13(10), 1998, pp. 1068-1071
A 65-year-old female received recombinant interferon (IFN) alpha-2b da
ily for the treatment of chronic hepatitis C. Fever (39 degrees C or h
igher) developed 14 days after the start of administration. Abdominal
computed tomography suggested multiple liver abscesses, which had not
been detected before IFN administration, An autopsy revealed an amoebi
c liver abscess. A subclinical infection of Entamoeba histolytica in t
his case developed into amoebic liver abscess during IFN administratio
n.