D-PENICILLAMINE TREATMENT FOR CHRONIC SENSORY ATAXIC NEUROPATHY ASSOCIATED WITH SJOGRENS-SYNDROME

Beneficial treatment has not been established for chronic sensory atax ic neuropathy associated with Sjogren's syndrome (CSAN-SS). We describ e two patients with CSAN-SS who clinically improved in response to D-p enicillamine treatment. Their neuropathic symptoms were lessened after D-penicillamine, and the results of electrophysiologic studies suppor t the clinical improvement. D-Penicillamine can be considered a potent ially beneficial agent in the treatment of CSAN-SS.