Ma. Weitzner et al., RELATIONSHIP BETWEEN QUALITY-OF-LIFE AND MOOD IN LONG-TERM SURVIVORS OF BREAST-CANCER TREATED WITH MASTECTOMY, Supportive care in cancer, 5(3), 1997, pp. 241-248
This study sought to compare the mood and quality of life (QOL) of bre
ast cancer survivors with those observed in low-risk breast cancer scr
eening patients. A group of long-term stage I-III breast cancer surviv
ors (n = 60) was compared with low-risk breast cancer screening patien
ts (n = 93) on measures of depression, anxiety, and QOL. Patients with
out a previous psychiatric history were studied. Although the groups d
iffered in age and education, correlations performed between age, educ
ation, and the outcome measures showed no association of age and educa
tion with the outcome measures. Breast cancer patients with stage III
disease showed significantly poorer functioning in all areas except fa
mily than did other breast cancer patients; however, when compared wit
h the breast cancer screening group, they showed higher QOL scores in
several domains. Higher mood scores were correlated with poorer scores
in all QOL areas except family functioning in the breast cancer group
. Only significantly elevated depression scores correlated with poorer
QOL areas in the breast cancer screening group. The psychological mea
sures were found to be more robust predictors of QOL than the demograp
hic variables in both the cancer and the screening patients. These res
ults suggest that longterm survivors of breast cancer continue to expe
rience significant stress and emotional distress, as evidenced by incr
eased depression and lower QOL functioning.