T. Yamaguchi et Hd. Dorfman, RADIOGRAPHIC AND HISTOLOGIC PATTERNS OF CALCIFICATION IN CHONDROMYXOID FIBROMA, Skeletal radiology, 27(10), 1998, pp. 559-564
Objective. To evaluate the frequency of radiologic and histologic mani
festations of matrix calcification in chondromyxoid fibromas. Patients
. Forty-four cases of chondromyxoid fibroma were reviewed. The age ran
ge of the patients was 3-70 years (average 29 years). Results. Calcifi
cation was found microscopically in 15 cases (34.1%). In five cases (1
2.5%) it was demonstrated on plain films or CT. The age range of the p
atients with microscopic evidence of calcified matrix was 14-70 years
(mean 46 years), while that of the patients with noncalcified lesions
was 3-59 years (average 21 years). All but two of the patients who sho
wed microscopic calcification in the tumors were over 40 years of age.
Four microscopic patterns of calcification were observed: coarse gran
ular, circumscribed, trabecular, and ''chicken-wire.'' Conclusions. Ca
lcification in chondromyxoid fibroma was found more frequently than in
previously reported studies. There was a tendency for this phenomenon
to occur in the tumors of older patients, particularly those over 40
years old, and in chondromyxoid fibromas situated in flat bones, inclu
ding ribs.