Ad. Durward et al., THE OUTCOME OF PATIENTS WITH UPPER AIRWAY-OBSTRUCTION TRANSPORTED TO A REGIONAL PEDIATRIC INTENSIVE-CARE UNIT, European journal of pediatrics, 157(11), 1998, pp. 907-911
The diagnoses, transfer, management and outcome of patients with upper
airway obstruction (UAO) admitted from district general hospitals (DG
H) to a regional paediatric intensive care unit were retrospectively r
eviewed over a 3.5-year period. Sixty-seven patient episodes were anal
ysed. Fifty-two cases (78%) underwent tracheal intubation prior to tra
nsport with a low morbidity for both procedures. The most common diagn
osis was viral croup (n = 34, 51%) with a median duration of intubatio
n of 5 days, with subglottic stenosis being the next most common categ
ory (n = 10, 15%), median duration of intubation 7 days. Inhaled budes
onide was used prior to intubation in 12 (35%) of those with croup, an
d inhaled bronchodilators in 28%, possibly reflecting diagnostic uncer
tainty. Patients with croup treated with budesonide were significantly
less likely to require intubation (P = 0.04). The re-intubation rate
for patients with viral croup was uncomfortably high at 16% (4/25) des
pite the routine use of prednisolone throughout the intubation period.
Successful extubation of patients with viral croup could not be predi
cted by age (P = 0.31), length of intubation (P = 0.94), endotracheal
tube size, (P = 0.60) abnormalities on the chest X-ray (P = 1.0), or p
resence of secondary bacterial infection (P = 0.23). Conclusion Althou
gh viral croup remains the most common diagnostic category presenting
at the DGH level with severe UAO, a wide range of other diagnoses is s
een. Despite clear evidence of benefit, steroid administration to chil
dren presenting at the DGH with viral croup has not become routine pra
ctice. Once intubated, no reliable predictors of successful extubation
were found amongst this patient group.