Ma. Ruiz et al., DETERMINATION OF THE STABILITY OF OMEPRAZOLE BY MEANS OF DIFFERENTIALSCANNING CALORIMETRY, JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 51(1), 1998, pp. 29-35
Differential scanning calorimetry was used to study the stability of o
meprazole in two forms: granules and powder. The drug was subjected to
light, elevated temperature (40 and 60 degrees C) and different pH va
lues. The greatest alterations in stability were caused by pH, followe
d by light.