OUTCOME OF IVF IN PATIENTS WITH ENDOMETRIOSIS IN COMPARISON WITH TUBAL-FACTOR INFERTILITY

Purpose: The aim of this retrospective study was to compare the outcom e of in vitro fertilization and embryo transfer in women with endometr iosis and a control group with tubal-factor infertility. Methods: Fort y-eight patients with endometriosis underwent 65 cycles of in vitro fe rtilization and embryo transfer at Huddinge University Hospital. The m arched control group with tubal-factor infertility consisted of 98 cyc les in 98 patients. These groups were retrospectively analyzed regardi ng stimulation,fertilization, embryo development,implantation, and pre gnancy outcome. Results: The fertilization rate was significantly lowe r in women with endometriosis, but the cleavage, implantation, and pre gnancy rates did not differ. Conclusions: Our results show that women with endometriosis have a lower fertilization rate compared with women with tubal;factor infertility However once the oocyte is fertilized, it seems that the preembryo has a normal chance of implantation, leadi ng to similar pregnancy rates.