Spatially explicit non-Mendelian diploid model

Citation
N. Lanchier, et C. Neuhauser,, Spatially explicit non-Mendelian diploid model, Annals of applied probability , 19(5), 2009, pp. 1880-1920
ISSN journal
10505164
Volume
19
Issue
5
Year of publication
2009
Pages
1880 - 1920
Database
ACNP
SICI code
Abstract
We introduce a spatially explicit model for the competition between type a and type b alleles. Each vertex of the d-dimensional integer lattice is occupied by a diploid individual, which is in one of three possible states or genotypes: aa, ab or bb. We are interested in the long-term behavior of the gene frequencies when Mendel.s law of segregation does not hold. This results in a voter type model depending on four parameters; each of these parameters measures the strength of competition between genes during meiosis. We prove that with or without a spatial structure, type a and type b alleles coexist at equilibrium when homozygotes are poor competitors. The inclusion of a spatial structure, however, reduces the parameter region where coexistence occurs.