PRENATAL-DIAGNOSIS OF A TRISOMY 17P DERIVED FROM A DE-NOVO NON-MOSAICSATELLITED MARKER

A trisomy 17pter --> p11.2 derived from a supernumerary de novo satell ited marker was identified by GTG bands and fluorescent in situ hybrid isation (FISH) in amniocytes of a fetus with malformations and intraut erine growth retardation (IUGR). At 39 weeks a male infant with a phen otype similar to other postnatal cases of 'pure' complete trisomy 17p was born. Some additional clinical features, however, make him more se verely affected than previous patients.